rat test subjects didn't get cancer, unlike the mice tested (pituitary adenoma and carcinoma, mammary gland adenocarcinoma, showing dose related effect at (0.1 to 0.6 and 1 to 5 times the maximum recommended human dose [MRHD] ). also,
In animal studies ziprasidone demonstrated developmental toxicity, including possible teratogenic effects at doses similar to human therapeutic doses. ...
In rats, embryofetal toxicity (decreased fetal weights, delayed skeletal ossification) was observed following administration of 10 to 160 mg/kg/day (0.5 to 8 times the MRHD on a mg/m2 basis) during organogenesis or throughout gestation, but there was no evidence of teratogenicity. Doses of 40 and 160 mg/kg/day (2 and 8 times the MRHD on a mg/m2 basis) were associated with maternal toxicity. The developmental no-effect dose was 5 mg/kg/day (0.2 times the MRHD on a mg/m2 basis).
There was an increase in the number of pups born dead and a decrease in postnatal survival through the first 4 days of lactation among the offspring of female rats treated during gestation and lactation with doses of 10 mg/kg/day (0.5 times the MRHD on a mg/m2 basis) or greater. Offspring developmental delays and neurobehavioral functional impairment were observed at doses of 5 mg/kg/day (0.2 times the MRHD on a mg/m2 basis) or greater. A no-effect level was not established for these effects."
lucky for me i only needed to know to get some potassium and magnesium in case my non-anxious chest pain was related to QT-prolongation and I am about to have a heart attack and die.
I am surprised they tested with such low doses.